
The final pair of undefeated teams in the NFL saw their perfect records broken during the fifth week as both the Philadelphia Eagles and Buffalo Bills suffered surprising home defeats.
Denver's football team evolved from underdogs to headline-makers following an spectacular comeback victory against the current Super Bowl title holders the Eagles, prior to boarding a plane for this Sunday's London contest.
New England's squad then traveled to Buffalo and halted Buffalo's undefeated start with an impressive victory of their own in their first primetime appearance in a full year.
The Baltimore Ravens experienced a third straight defeat - their defensive unit's struggles could be terminal for their postseason hopes - while Dallas, Indianapolis, and Detroit enjoyed blowout wins on another action-packed Sunday.
It wasn't just beating the Super Bowl champions, but the manner of their comeback from 14 points down that made the Broncos' win by 21-17 in Philadelphia such a signature success.
The Eagles had won 10 games consecutively, 12 straight on home turf and 20 out of 21 total before Broncos quarterback Bo Nix engineered two scoring drives in five fourth-quarter minutes and a last-minute field goal.
The Eagles are now 4-1 but there exists a big worry about their offensive unit, which sits among the poorest performing in the league. Receiver DaVonta Smith stated they are not "on the same page" with quarterback Jalen Hurts.
The Broncos' defensive unit, which sacked Hurts six times, had much to contribute with it, and, together with an established starting QB in Nix and elite coach in Sean Payton, they possess all the components to mount a serious challenge.
Denver meet New York's Jets at Tottenham Stadium on Sunday.
If Denver's win was somewhat anticipated, few predicted New England marching into Buffalo and beating Josh Allen's Bills, but they accomplished it with tremendous resilience.
Their initial national television appearance for Drake Maye delivered a breakout performance as he directed a decisive field goal drive in the dying seconds to secure victory 23-20.
Maye was tough and made the right throws at the right times, several to ex-Buffalo wideout Stefon Diggs, who had an outstanding performance for their coach's team.
The head coach was anticipated to turn things around in New England, but a win like this arrived earlier than many predicted.

The Patriots defence contained Buffalo's offensive efforts during their surprising road victory.
This campaign is becoming a disaster for Baltimore, who were without a host of key defenders as they were hammered 44-10 by the Houston Texans.
It equaled their largest loss at home, and dropping to 1-4 for the season means one of the preseason Super Bowl favourites have only a slim chance of making the postseason.
The Ravens are currently 4-11 playing without superstar quarterback Lamar Jackson, who was injured, but it is an exceptionally poor defense that is the real problem - for a franchise that have been synonymous with stout defense historically.
The Texans coasted to victory as the Ravens became the initial squad in modern NFL history to allow at least 37 points in four of their first five contests. Their season is effectively in tatters.
The Lions' running back duo Gibbs and Montgomery scored six points in one contest for the 14th time - a joint NFL record - as the Lions defeated Cincinnati 37-24.
Victory made it four wins in a row for the league's top scorers the Lions, but none against opponents with positive records.
A more surprising 4-1 team are the Indianapolis Colts. With their star running back running in three touchdowns in their decisive hammering of Las Vegas and signal-caller Daniel Jones looking like a transformed player, they will be a tough match for any side.
The Tampa Bay Buccaneers joined the four-win group with a thrilling 38-35 victory in Seattle in which both teams exchanged nine touchdowns in 10 sparkling possessions before Seattle faltered initially with a late turnover.
Chase McLaughlin booted the winner with the final play of the contest for his second occasion this season. Each of the Bucs' wins have been secured in the final moments.
The way New Orleans and Tennessee started this campaign, they needed help to secure their initial victories, and they got plenty thanks to some farcical errors from the New York Giants and Arizona.
After a good start from New York rookie Jaxson Dart, the Giants made five giveaways - one was decisively returned for a touchdown - while also allowing Rashid Shaheed to find the end zone on a long reception as New Orleans won 26-14.
The Cardinals were even worse as they squandered a 21-3 lead primarily due to two huge mistakes.
First, Emari Demercado unexplainably fumbled the ball moments before reaching the end zone for a 72-yard score.
More disastrous followed when the Cardinals intercepted Cam Ward close to their own goal line, then lost the football into the end zone for Tyler Lockett to score as the Titans snapped a 10-game losing streak with a 22-21 victory.

The receiver registered among the most bizarre scores we'll see this year.
That left the Jets as the only winless team left in the league after their punishing 37-22 defeat by Dallas.
The quarterback became the first player in NFL history to eclipse 4K through the air and 1K on the ground in his first 20 career games as he returned from injury to guide the Washington Commanders to a notable 27-10 win at Los Angeles.
The running back was the star man for Carolina with over 200 yards on the ground in their exciting 27-24 victory over the Miami Dolphins.
Minnesota Vikings 21-17 Cleveland Browns
Houston Texans 44-10 Baltimore Ravens
Miami Dolphins 24-27 Carolina Panthers
Las Vegas Raiders 6-40 Indianapolis Colts
New York Giants 14-26 New Orleans Saints
Dallas Cowboys 37-22 New York Jets
Denver Broncos 21-17 Philadelphia Eagles
Tennessee Titans 22-21 Arizona Cardinals
Tampa Bay Buccaneers 38-35 Seattle Seahawks
Detroit Lions 37-24 Cincinnati Bengals
Washington Commanders 27-10 Los Angeles Chargers
New England Patriots 23-20 Buffalo Bills
San Francisco 49ers 26-23 Los Angeles Rams (OT)
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